- Darren Dunn
- Posts
- The Seven Psychedelic Safeties: Beyond Set and Setting
The Seven Psychedelic Safeties: Beyond Set and Setting
Essential wisdom for the modern psychedelic journey

For decades, they were demonized and pushed underground. Now, psychedelics are emerging as one of the most promising breakthroughs in mental health care. Clinical trials are showing unprecedented results for depression, PTSD, and end-of-life anxiety. Popular media is exploring their potential. Even major corporations are investing in psychedelic research. The conversation is shifting from "if" to "when" these tools will be widely available.
But there's a critical problem.
While interest in psychedelics soars, access to safe, legal experiences remains severely limited. Unless you're facing end-of-life anxiety, have treatment-resistant depression, or qualify for PTSD studies, your options for legal psychedelic therapy are practically non-existent.
This creates a dangerous gap. People are increasingly turning to underground channels or self-guided experiences, often without proper education or support. They're seeking healing and transformation but lacking the knowledge to maximize benefits and minimize risks.
The current situation forces people to choose between waiting years for legal access or navigating these powerful experiences without proper guidance. Neither option is ideal.
And here's what's particularly frustrating: There are people like myself who have spent years studying these medicines, understanding their proper use, and developing protocols for safe experiences. We've built relationships with these tools, learned from both successes and challenges, and gathered wisdom that could help others. But the illegality of these substances makes sharing this knowledge complicated and rare.
The result? Powerful tools for healing and growth are being used without proper preparation, increasing the risk of challenging experiences or missed opportunities for transformation.
This needs to change.
While we can't alter the legal landscape overnight, we can share essential knowledge about safe and intentional use. Drawing from modern research, ancient wisdom, and personal experience, I want to offer a comprehensive framework for approaching these experiences responsibly.
This framework is called The Seven Psychedelic Safeties. It combines the methodologies from great psychedelic thinkers like Timothy Learly, James Fadiman, and Darren Dunn (manifestation in progress).
The Seven Safeties
Each Safety represents a critical dimension of preparation and practice, designed to help you maximize the benefits of these powerful tools while minimizing risks. Think of these Safeties not as rigid rules, but as interconnected elements of a complete approach to psychedelic work. When one element is missing or weak, the entire container becomes less secure. But when all seven elements are strong and in harmony, they create the conditions for profound and lasting transformation.
Understanding and implementing these Safeties will help you navigate psychedelic experiences with greater confidence and clarity. Let's dive into each one.
1. Screening - Know Yourself First
Think of screening as your foundation. Just as you wouldn't build a house without checking the ground beneath it, you shouldn't approach psychedelics without understanding your baseline. This goes beyond just checking boxes – it's about honest self-assessment.
Essential screening considerations include:
personal or family history of psychosis
current or past bipolar disorder
severe anxiety conditions
heart conditions
current medications (especially SSRIs)
unprocessed trauma
pregnancy or breastfeeding
Medications, particularly psychiatric ones, can create significant risks. SSRIs, which many people take for depression and anxiety, work on the same neurotransmitter systems as most psychedelics. This isn't just about reduced effects – it's about potential safety risks. Similarly, Monoamine oxidase inhibitors (MAOIs) can create dangerous interactions, while antipsychotics and lithium present their own specific concerns.
Always consult with a healthcare provider you trust before considering any changes to your medication regimen. This isn't about gatekeeping – it's about ensuring your safety and setting you up for a beneficial experience.
2. Set - Your Mental and Emotional Landscape
Your mindset is not just another checkbox on a preparation list. It is the foundation that shapes your entire journey. The thoughts, emotions, and intentions you bring will profoundly influence what unfolds. A clear and prepared mind transforms a psychedelic experience into an opportunity for deep healing and growth.
Key mindset elements to consider:
current life stability
clear intentions for the experience
realistic expectations
psychological readiness
available time for integration
a circle of supportive relationships
The key to proper "set" is honesty with yourself. Where are you emotionally? What's calling you to this experience? Are you in a period of relative stability, or are you facing major life changes? These questions aren't about finding perfect conditions – they're about being prepared for what might arise. The medicine often shows us what we need to see, not necessarily what we want to see.
3. Setting - Creating Your Container
Setting isn't just about having a comfortable room – it's about creating a container that supports and protects your journey. Think of it as creating a sacred space, even if temporary. Your environment should feel safe, comfortable, and free from potential interruptions.
Essential elements for your space:
private, secure location
access to nature if possible
comfortable areas for different positions
easy access to water and bathroom
appropriate music options
basic comfort items (blankets, eye mask)
fresh air and natural light if possible
The ideal setting combines physical comfort with emotional safety. The space should be clean and uncluttered, with different areas for sitting, lying down, and moving around. Consider the atmosphere too – gentle lighting, fresh air, and a carefully chosen music playlist can significantly influence your journey. Have essentials within easy reach.
Let me share a personal story that illustrates the critical importance of setting. Early in my journey, I made the mistake of taking mushrooms at an immersive Van Gogh exhibit. It seemed like a great idea at the time – beautiful art, music, a cultural experience. But I hadn't properly respected the power of setting. The combination of the crowd, the intense music, and the massive moving projections quickly became overwhelming.
What I thought would be magical turned into sensory overload, triggering a panic attack. A space that would have been wonderful sober became incredibly challenging under the influence of psychedelics.
4. Substance - Know What You're Working With
Understanding your substance is non-negotiable. This isn't just about identifying what you're taking – it's about developing a deep respect for the medicine's power and potential. Every psychedelic has its own character, timeline, and optimal conditions for use. Just as a doctor wouldn't prescribe medication without understanding its effects, you shouldn't work with psychedelics without thoroughly knowing their nature.
Critical substance knowledge includes:
specific compound and its effects
appropriate dosage for your experience level
onset time and total duration
common interactions
storage requirements
testing your substance to ensure safety
Start low, especially if you're new to psychedelics. The relationship between dose and effect isn't always linear, and smaller doses can often provide profound insights while maintaining more control over the experience. Above all else, TEST YOUR SUBSTANCES. This isn't optional or just a 'best practice' – it's an absolute necessity. Testing kits are legal, affordable, and could save your life.
The future of psychedelic medicine is coming. Soon, like cannabis in Canada, we'll have access to legally produced, laboratory-tested medicines for healing and growth. But we're not there yet. Until that day comes, testing your substances isn't just responsible – it's essential. Your life is worth more than convenience. Your safety is worth more than blind trust. Test every time, no exceptions.
5. Sitter - Your Trusted Guardian
Having a sitter or guide might be the most important safety factor, and I speak from deep personal experience here. My wife has been my most trusted sitter throughout my journey with these medicines. She embodies everything you should look for in a guide: deeply trustworthy, genuinely supportive of the healing journey, and gifted with an intuitive understanding of when to offer support and when to encourage internal exploration. Also, my dog is there for the extra snuggles.
Essential sitter qualities:
deep trustworthiness
ability to remain sober and present
calm and grounding presence
non-judgmental attitude
understanding of your healing intention
intuitive sense of when to help
respect for boundaries
experience with holding space
While experience with psychedelics can be valuable, what's most important is finding someone like my wife – someone who combines deep trust, genuine care, and an understanding that you're undertaking this journey for personal transformation. They should be open-minded enough to support your exploration while being grounded enough to maintain safety and stability.
6. Session - The Journey Itself
The session requires a clear container of time. The most effective approach is the three-day protocol such as Friday, Saturday, Sunday
Friday (Day Before): Keep your day chill. Maybe take the day off work. Focus on winding down and getting your space ready.
Saturday (Day of Journey): This is sacred time. The entire day belongs to the experience, from sunrise to sleep.
Sunday (Day After): A day for gentle re-entry. No commitments, no obligations, no exceptions. Think about going for a nice long walk, not about starting a new home renovation project.
Essential timing considerations:
block all three days completely in your calendar
avoid technology and devices
no "maybe" plans or tentative commitments
no watching the clock during the experience
no rushing back to obligations the next day
All technology should be turned off for the duration. No phones, no laptops, no notifications pulling at your attention. This isn't just about avoiding distractions – it's about creating an undisturbed space where you can fully immerse in the experience.
The only thing on your calendar for these three days should be the journey itself. Time pressure is the enemy of a deep experience – eliminate it completely.
7. Support - The Integration Period
Integration isn't an afterthought – it's where the real work happens. Think of the experience as planting seeds; integration is tending the garden. The days and weeks following your journey are crucial for transforming insights into lasting change.
Key integration practices:
journaling and reflection
time in nature
gentle movement (yoga, walking)
meditation or mindfulness
community connection
creative expression
professional support if needed
gradual implementation of insights
The immediate days after your experience should be gentle. Keep social interaction minimal, spend time in nature, journal about your insights, and give yourself space to process. Regular practices like meditation, movement, and community connection can help anchor your insights. Consider joining integration circles or finding others who understand these experiences. The psychedelic community can provide valuable perspectives and support during this crucial phase.
The 10% Rule
One of the most important principles I've learned in my years of working with psychedelics is what I call The 10% Rule. After a profound psychedelic experience, aim to implement only about 10% change in your life. This might sound overly conservative, especially when you've just had insights that make you want to transform everything at once. But there's deep wisdom in this approach.
Why 10%? Because sustainable transformation happens gradually. When we try to change everything at once, we often trigger resistance in ourselves and our environments, leading to burnout and regression. But when we focus on implementing just 10% of our insights:
changes are more likely to stick
we avoid overwhelming ourselves
our support systems can adjust gradually
we maintain stability while growing
we can build on small successes
Think of it like building muscle – trying to lift too much too soon leads to injury. But consistent, manageable progress leads to lasting strength. The same applies to psychological and spiritual growth.
Looking Ahead
I'm excited to announce that I'm working on a comprehensive manual for preparing for a transformative high-dose experience, which I'll be sharing for free with this community. This detailed guide will expand on each of these principles and provide step-by-step preparation protocols. Stay tuned.
To be absolutely clear: I do not provide substances or connections to sources. My role is to offer preparation guidance, integration support, and harm reduction education. If you're interested in working together, I offer free discovery calls to discuss how I can support your journey
A Final Note on Responsibility
While research shows psychedelics to be physically safe (when properly screened), they demand respect and careful preparation. They're not recreational tools or quick fixes. They're powerful catalysts for healing and growth when approached with intention and care.
My mission is to share everything I've learned to help others approach these experiences safely and meaningfully. The psychedelic renaissance is here, but its success depends on our collective commitment to responsible use.
With care and respect,
Darren
---
PS: This information is for harm reduction and educational purposes only. I encourage everyone to stay informed about and compliant with their local laws regarding psychedelic substances.
Want to discuss your psychedelic journey? Book a free discovery call.